How to verify authentic Rejuran and the planned volume
* Product verification: At Min Clinic, the selected genuine Rejuran product is opened in front of the patient before treatment. The clinic’s authenticity certificates are also displayed on site. * Product selection: Rejuran is not a single uniform product. The product should be selected according to the treatment area, skin condition, and sensitivity to discomfort. * Clear dosing: Treatment plans are explained by the injected volume in cc. REJURAN Healer and REJURAN HB are available in 2cc or 4cc treatment plans, while REJURAN i is available as a 1cc treatment for the eye area. * Doctor-performed injections: Rejuran is manually injected by a doctor at Min Clinic. The injection areas and distribution are planned according to the patient’s skin condition and treatment goals.
Before treatment, confirm the exact product name and planned volume rather than relying on broad descriptions such as “full dose.”
Understanding the different Rejuran products
Rejuran products are manufactured by PharmaResearch Co., Ltd. in Korea. Min Clinic distinguishes among the following products:
* REJURAN®: A PN-based product commonly used for the overall face to manage fine lines, skin texture, and elasticity. * REJURAN® HB: Contains PN, hyaluronic acid, and lidocaine. The hyaluronic acid supports hydration, while lidocaine helps reduce injection discomfort. * REJURAN HB plus®: Contains PN, hyaluronic acid, and lidocaine but is a separate product from REJURAN HB. * REJURAN® i: A PN-based product introduced by the manufacturer for use around the thinner skin of the eye area.
The doctor selects the appropriate product and volume after assessing the patient’s skin condition, treatment area, and sensitivity.
What to expect when scheduling treatment on a workday
A visit at Min Clinic begins with an initial consultation with a senior consultation manager and a skin assessment using the EVE V MUSE analyzer. This is followed by an assessment and consultation with the doctor.
Consultation time varies depending on the patient’s questions and condition, but patients should generally allow approximately 15 to 30 minutes. International consultations may take longer when interpretation or a more detailed explanation is required.
Same-day treatment may be possible depending on appointment availability and the doctor’s assessment. Skin assessment, cleansing, and topical anesthetic cream are included before treatment.
Rejuran does not require formal medical leave for every patient, but visible bumps, redness, swelling, tenderness, or bruising may affect work and social schedules. If you have an important meeting or event, allow enough recovery time rather than assuming there will be no visible signs.
Dosing and scheduling
Rejuran pricing and treatment planning are based on the specific product and injected volume in cc.
Typical options at Min Clinic include:
* REJURAN Healer: 2cc or 4cc * REJURAN HB: 2cc or 4cc * REJURAN i: 1cc for the eye area * REJURAN HB plus: Treated as a separate product from REJURAN HB
The doctor determines the product, treatment area, and volume after assessing the patient’s skin.
For a single treatment, an interval of approximately 12 weeks may be recommended before another session. For intensive care, a series of three treatments at two-week intervals may be recommended. The appropriate number of sessions and interval may vary according to skin condition and treatment goals.
Changes may begin to become noticeable approximately one to two weeks after treatment. Results vary among individuals and may last approximately three to six months, depending on skin type, condition, and lifestyle.
Downtime and aftercare
Temporary skin reactions may occur after Rejuran injections.
* Small raised bumps or injection marks: Usually settle within approximately three days but may remain for up to one week depending on the individual. * Redness, mild swelling, and tenderness: Usually improve within several days but may continue for approximately one week. * Bruising: If it occurs, it may remain for approximately one to two weeks. * Cleansing and makeup: Generally possible from the following day. * Strenuous exercise and sauna use: Resume after at least three days. * Flying: Generally possible on the day of treatment if there are no unusual symptoms.
Common temporary reactions include injection discomfort, raised bumps, redness, swelling, bruising, itching, and tenderness.
Less common but important reactions may include persistent nodules or firmness, inflammation, infection, discoloration, herpes reactivation, and allergic reactions. REJURAN HB and REJURAN HB plus contain lidocaine, so patients with a history of sensitivity to lidocaine or other amide-type local anesthetics should tell the doctor before treatment.
Contact the clinic if symptoms are severe, continue longer than expected, or cause concern.
When Rejuran may not be appropriate
Tell the clinic before treatment if you:
* Are pregnant or breastfeeding * Have a known sensitivity to any product ingredient * Have inflammation, infection, herpes, or an open wound in the treatment area * Have a history of allergic reactions to injectable products * Are sensitive to lidocaine or other amide-type local anesthetics, particularly when considering REJURAN HB or REJURAN HB plus * Are currently taking medication that may affect treatment or recovery * Recently received another injectable treatment in the same area
Min Clinic does not perform medical aesthetic procedures during pregnancy. Skincare treatments may be available after consultation.
Price and payment information
Rejuran pricing is based on the selected product and injected volume in cc. Skin assessment, cleansing, and topical anesthetic cream are included.
VAT is charged separately from the listed price at the applicable statutory rate. In accordance with Korean tax law, VAT refunds for cosmetic medical services provided to foreign visitors are no longer available for treatments received on or after January 1, 2026. Min Clinic therefore does not process VAT refunds for treatments received from that date onward.
Min Clinic applies the same prices to international and Korean patients and does not charge an additional card-processing fee.
Accepted payment methods include:
* Visa * Mastercard * American Express * UnionPay * JCB * Apple Pay * WeChat Pay * Alipay * Cash in Korean won
PayPal is not accepted. Payment may be split across two cards.
Who performs Rejuran at Min Clinic?
Three doctors practice at Min Clinic, two of whom are board-certified specialists. Medical aesthetic procedures, including Rejuran injections, are performed by a doctor. Skincare treatments are provided separately.
Young Soo Min, chief medical director, is an adjunct professor at Hanyang University and formerly served as deputy director of the Gangnam Station branch of NB Clinic. His manufacturer-issued plaques include Top Restylane Injector from Galderma in 2012, Top Radiesse Injector from Merz in 2011, and IDP Specialist from Allergan in 2011.
Min Ji Kim, medical director, is a board-certified specialist and a former director of Apgujeong ORACLE Dermatology Clinic. She has also participated in academic exchanges with clinics in Japan.
Chan Ho Jung, medical director, graduated from the College of Pharmacy at Sungkyunkwan University and the College of Medicine at Hanyang University. He completed his residency at Hanyang University Medical Center and was named a Restylane Expert Injector by Galderma.
For Rejuran, the doctor assesses the patient’s skin condition and treatment area, selects the appropriate product and volume, and performs the injections.
Getting here from Sinsa Station
If you are coming from Sinsa Station near Garosu-gil, you can travel by subway or taxi.
* Subway: Take the Shinbundang Line from Sinsa Station to Nonhyeon Station, transfer to Line 7, and continue to Gangnam-gu Office Station. Travel time may vary depending on transfers and walking time. * Taxi: The clinic is located east of Sinsa Station along Dosan-daero. Travel time and fare vary depending on traffic, the selected route, tolls, and late-night surcharges.
The clinic is located on the fourth floor of Daedong Tower at 326 Dosan-daero, near Hakdong Intersection. An Olive Young store is located on the ground floor.
* From Apgujeong Rodeo Station: Use Exit 5 of the Suin–Bundang Line. * From Gangnam-gu Office Station: Use Exit 3 or 3-1. * Parking: The outdoor parking lot is on the first floor of Daedong Tower. Enter from the alley to the right of the Olive Young store. Valet parking is available. Contact the clinic for current parking information.
Evidence and expectations
Rejuran is a PN-based injectable product. PN is administered into the skin to support the management of fine lines, skin texture, and elasticity.
A 2025 systematic review published in the Journal of Cosmetic Dermatology examined nine studies involving 219 patients who received PN treatments. The included studies were rated as low to moderate in quality, and the injection areas and techniques varied.
The review reported promising findings related to wrinkles, skin texture, and elasticity but also found limited agreement on the optimal use of PN treatments. The authors concluded that more rigorous, high-quality studies are needed to confirm effectiveness and safety.
This review evaluated PN treatments in aesthetic medicine broadly and should not be interpreted as evidence concerning only one specific Rejuran product.
When deciding whether to proceed, consider the doctor’s assessment, the exact Rejuran product, the planned volume in cc, the treatment interval, possible downtime, and the clinic’s follow-up guidance.
Practical information
Clinic hours:
* Monday–Thursday: 10:00–19:00 * Friday: 10:00–20:00 * Saturday: 10:00–15:00 * Lunch break: 13:00–14:00 * Closed on Sundays and public holidays
Appointments can be arranged through WhatsApp, KakaoTalk, or WeChat. English consultations are provided by the senior consultation manager together with an interpreter by appointment. Chinese and Japanese language assistance is also available.
Contact information:
* Clinic phone: +82-2-515-2119 * English WhatsApp: +82-10-3379-9350 * WhatsApp: https://api.whatsapp.com/message/2P2LPJESWKZTE1?autoload=1&app_absent=0 * KakaoTalk: https://pf.kakao.com/_pxgTqE * WeChat: minbeauty * LINE: minclinic * Website: https://www.min-clinic.co.kr/
WhatsApp messages are answered during clinic hours, and the clinic responds as promptly as possible. Bring a passport or another form of photo identification to your appointment.
Skin analysis results and treatment records are both available upon request. Skin analysis results can be sent by email, and treatment records can be provided as an itemized treatment statement.
Frequently asked questions
How can I confirm that genuine Rejuran is being used?
At Min Clinic, the selected genuine Rejuran product is opened in front of the patient before treatment. The clinic’s authenticity certificates are also displayed on site. The exact product and planned volume in cc are explained before treatment.
What is the difference between the Rejuran products?
REJURAN is PN-based and is commonly used for the overall face. REJURAN HB and REJURAN HB plus contain PN, hyaluronic acid, and lidocaine, but they are separate products. REJURAN i is a PN-based product intended for the thinner skin around the eye area. The doctor selects the product according to the patient’s skin condition, treatment area, and sensitivity.
Who performs the injections?
Rejuran injections at Min Clinic are performed manually by a doctor. Skincare treatments are provided separately.
Can I have a consultation and treatment on the same day?
Same-day treatment may be possible depending on appointment availability and the doctor’s assessment. The visit begins with a consultation with a senior consultation manager and an EVE V MUSE skin assessment, followed by the doctor’s assessment and treatment planning.
How often are Rejuran treatments scheduled?
For a single treatment, another session may be considered after approximately 12 weeks. For intensive care, a series of three treatments at two-week intervals may be recommended. The appropriate schedule depends on the patient’s skin condition and treatment goals.
When will I notice changes, and how long may they last?
Changes may begin to become noticeable approximately one to two weeks after treatment. The duration varies, but results may last approximately three to six months depending on the patient’s skin condition, skin type, and lifestyle.
Can I go to work the next day?
Many patients can return to their usual schedule, but visible raised bumps, injection marks, redness, swelling, tenderness, or bruising may remain. Cleansing and makeup are generally possible from the following day. If you have an important event or meeting, allow additional recovery time.
Can I fly after Rejuran?
Flying is generally possible on the day of treatment if there are no unusual symptoms. Tell the clinic about your travel schedule during the consultation.
Can I receive Rejuran during pregnancy?
No. Min Clinic does not perform medical aesthetic procedures during pregnancy. Skincare treatments may be available after consultation.
What does the current scientific evidence say?
A 2025 systematic review of PN treatments included nine studies involving 219 patients. The evidence was rated as low to moderate in quality, and treatment methods varied. The findings were promising, but the authors reported limited consensus regarding optimal use and recommended further high-quality research.
Sources
* Lampridou et al., The Effectiveness of Polynucleotides in Esthetic Medicine: A Systematic Review, Journal of Cosmetic Dermatology, 2025 — https://pubmed.ncbi.nlm.nih.gov/39645667/ (checked 2026-09-05) * Min Clinic official website — https://min-clinic.co.kr/en/ (checked 2026-09-09) * Min Clinic contact page — https://min-clinic.co.kr/contact/ * Seoul Metropolitan Government transportation information — https://news.seoul.go.kr/traffic/archives/1659
